DOI:

10.37988/1811-153X_2026_2_16

Influence of vitamin D on periodontal disease and caries resistance formation: a literature review

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Authors

  • E.M. Razmakhnina 1, PhD in Medical Sciences, associate professor of the Pediatric dentistry Department
    ORCID: 0000-0002-6263-0169
  • A.G. Kostritsyn 1, assistant at the Paediatric dentistry Department
    ORCID: 0000-0002-5931-7745
  • N.A. Saveleva 1, 4th year student at the Dental Faculty
    ORCID: 0009-0005-5352-8591
  • N.K. Zaporozhets 2, first-year postgraduate student in Dentistry
    ORCID: 0009-0001-0440-6708
  • K.B. Zaporozhets 1, senior lecturer at the Prosthodontics Department
    ORCID: 0009-0007-3635-7377
  • 1 Kemerovo State Medical University, 650056, Kemerovo, Russia
  • 2 Kemerovo State University, 650000, Kemerovo, Russia

Abstract

Currently, the biological effects of vitamin D are being widely studied in various fields of medicine. Dentistry is no exception: it has been established that vitamin D can affect the disease incidence of periodontal tissues and the formation of caries resistance. The aim of the review is a studying scientific literature data about the effect of vitamin D on periodontal tissue disease and the formation of oral caries resistance. In the course of the analysis of 53 sources, it was found that vitamin D is involved in amelogenesis, dentinogenesis, mineralization of dental tissues, and also forms immunity of the oral cavity.
Conclusion.
Oral vitamin D supplements appear to have a preventive effect on inflammatory periodontal diseases and dental hard tissues, but further research is needed in this area.

Key words:

vitamin D, calcitriol, caries resistance, periodontium

For Citation

[1]
Razmakhnina E.M., Kostritsyn A.G., Saveleva N.A., Zaporozhets N.K., Zaporozhets K.B. Influence of vitamin D on periodontal disease and caries resistance formation: a literature review. Clinical Dentistry (Russia).  2026; 29 (2): 16—22. DOI: 10.37988/1811-153X_2026_2_16

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Received

July 8, 2025

Accepted

May 8, 2026

Published on

July 4, 2026