DOI:

10.37988/1811-153X_2024_4_160

Application of a new medical device for the treatment of purulent wounds in the maxillofacial region

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Authors

  • K.O. Fedorova 1, postgraduate at the Maxillofacial surgery Department
    ORCID: 0009-0007-7466-7958
  • M.S. Krasnov 2, PhD in Biology, senior researcher at the Laboratory of Biopolymer Cryochemistry
    ORCID: 0000-0001-5057-7295
  • A.I. Shaykhaliev 1, Doctor of Science in Medicine, professor of the Maxillofacial surgery Department
    ORCID: 0000-0002-4920-7171
  • A.M. Isagadzhiev 1, postgraduate at the Maxillofacial surgery Department
    ORCID: 0000-0001-5395-3997
  • V.I. Lozinsky 2, Doctor of Science in Chemistry, professor, chief researcher of the Biopolymer cryochemistry Lab
    ORCID: 0000-0002-8111-1161
  • O.Yu. Kolosova 2, PhD in Chemical sciences, senior researcher at the Biopolymer cryochemistry Lab
    ORCID: 0000-0002-0378-3464
  • 1 Sechenov University, 119991, Moscow, Russia
  • 2 Nesmeyanov Institute of Organoelement Compounds, 119334, Moscow, Russia

Abstract

In this study, we would like to present a new medical device for wound treatment. It is a polyvinyl alcohol cryogel with through channels of a certain diameter and length to drain exudate from the wound and contains antibiotics and antimycotics to suppress infection in the wound. The modulus of elasticity of this polyvinyl alcohol cryogel-based medical device ranges from 5 to 50 kPa, where these values are the most optimal for treating various types of defects. This medical device was applied in the clinic in the treatment of patients with purulent-inflammatory diseases of the maxillofacial region. As a result of studies, excellent drainage properties of the new medical device, its expressed antimicrobial effect in the wound, stability, atraumaticity and convenience in its application were noted.

Key words:

drainage, wounds, dressings for wounds, cryogel

For Citation

[1]
Fedorova K.O., Krasnov M.S., Shaykhaliev A.I., Isagadzhiev A.M., Lozinsky V.I., Kolosova O.Yu. Application of a new medical device for the treatment of purulent wounds in the maxillofacial region. Clinical Dentistry (Russia).  2024; 27 (4): 160—165. DOI: 10.37988/1811-153X_2024_4_160

References

  1. Tazin D.I., Shakirov M.N., Tazin I.D., Pleshko R.I. Application of sorption technologies in complex treatment of purulent-inflammatory diseases of the maxillofacial area. Avicenna Bulletin. 2018; 1: 77—83 (In Russian). eLIBRARY ID: 35386545
  2. Shakirov M.N., Tazin I.D., Yul’Chiev R.I., Tazin D.I., Prozorova N.V., Dzhonibekova R.N., Hushvahtov D.D. Application of the innovative sorption bandage “Vita Vallis” in the comprehensive treatment of patients with purulent inflammatory processes of the maxillofacial region. Orenburg Medical Bulletin. 2020; 1 (29): 25—32 (In Russian). eLIBRARY ID: 42553375
  3. Vinnik Y.S., Markelova N.M., Tyuryumin V.S. Modern methods of septic wounds treatment. Siberian Medical Review. 2013; 1 (79): 18—24 (In Russian). eLIBRARY ID: 20466609
  4. Eckstein F.M., Pinsel V., Wurm M.C., Wilkerling A., Dietrich E.M., Kreißel S., von W.Ilmowsky C., Schlittenbauer T. Antiseptic negative pressure instillation therapy for the treatment of septic wound healing deficits in oral and maxillofacial surgery. J Craniomaxillofac Surg. 2019; 47 (3): 389—393. PMID: 30638743
  5. Yang Y.H., Jeng S.F., Hsieh C.H., Feng G.M., Chen C.C. Vacuum-assisted closure for complicated wounds in head and neck region after reconstruction. J Plast Reconstr Aesthet Surg. 2013; 66 (8): e209—16. PMID: 23578735
  6. Tyuryumin V.S., Malkov A.B., Gorbunov N.S., Samotesov P.A., Kasparov E.V. Flow-transmembrane dialysis complex. Siberian Medical Review. 2007; 4 (45): 45—47 (In Russian). eLIBRARY ID: 15609296
  7. Shajkhaliev A.I., Korshakov E.V., Kolosova O.Yu., Krasnov M.S., Lozinskij V.I. Temporary implant for patients with infected defects in the maxillofacial region and a method for treating them using such an implant. Patent RU no. 2729929, effective from 18.02.2020 (In Russian).
  8. Lozinsky V.I., Damshkaln L.G., Kurochkin I.N., Kurochkin I.N. Study of cryostructuring of polymer systems: 28. Physicochemical properties and morphology of poly (vinyl alcohol) cryogels formed by multiple freezing-thawing. Colloid Journal. 2008; 70 (2): 189—198. DOI: 10.1134/S1061933X08020117
  9. Lozinsky V.I., Damshkaln L.G., Shaskolsky B.L., Babushkina T.A., Kurochkin I.N., Kurochkin I.I. Study of cryostructuring of polymer systems: 27. Physicochemical properties of poly (vinyl alcohol) cryogels and specific features of their macroporous morphology. Colloid Journal. 2007; 69: 747—764. DOI: 10.1134/S1061933X07060117
  10. Razavi M., Qiao Y., Thakor A.S. Three-dimensional cryogels for biomedical applications. J Biomed Mater Res A. 2019; 107 (12): 2736—2755. PMID: 31408265
  11. Lozinsky V.I. Cryotropic gelation of poly (vinyl alcohol) solutions. Russian Chemical Reviews. 1998; 7: 573—586. DOI: 10.1070/RC1998v067n07ABEH000399
  12. Lozinsky V.I., Okay O. Basic principles of cryotropic gelation. In: Okay O. (ed) Polymeric cryogels. Advances in polymer science. Cham: Springer, 2014. Pp. 49—101. DOI: 10.1007/978-3-319-05846-7_2

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Received

February 14, 2024

Accepted

October 28, 2024

Published on

December 17, 2024