Clinical and functional rationale for the treatment of chronic generalized periodontitis using PDT

Abstract

Objectives — increasing the effectiveness of treatment of inflammatory periodontal diseases based on the photodynamic effect on the clinical and functional state of the periodontium.
Materials and methods.
Treatment of chronic generalized periodontitis of medium degree in 58 people (23 men and 35 women) from 40 to 60 years old was carried out. The patients were divided into 2 groups depending on the type of treatment: in the group I of 30 patients photodynamic therapy (PDT) with 1% dimegin gel (660 nm, 95 J/cm2) was applied, in the control group II of 28 patients standard treatment without PDT was carried out. In all patients the values of hygienic Green—Vermillion index (OHI-S), Mühlemann bleeding index (SBI) and periodontal index were determined. Linear systolic (Vas) and mean (Vam) blood flow velocity, volumetric systolic (Qas) and mean (Qam) blood flow velocity, peripheral resistance index (RI) and pulsatility index (PI) were determined by Doppler ultrasonography.
Results.
After PDT in group I, OHI-S, PI and SBI values decreased by 8.2, 2.8 and 2.2 times, respectively, which was maintained after 6 and 12 months. In group II, the positive dynamics of clinical indices was less pronounced and persisted up to 3 months with subsequent deterioration of the indices after 6 and 12 months. In group I after PDT with dimegin Vas and Qas increased by 55.8 and 52%, respectively, which characterizes the normalization of microcirculation in periodontal tissues.
Conclusion.
PDT with 1% dimegin gel has an effective effect on microhemodynamics in periodontal tissues.