DOI:

10.37988/1811-153X_2024_2_22

Clinical and laboratory effectiveness of exogenous prevention and treatment of focal enamel demineralization in children

Downloads

Authors

  • G.I. Skripkina 1, PhD in Medical Sciences, associate professor and head of the Pediatric dentistry Department
    ORCID ID: 0000-0001-7783-6111
  • O.V. Matskieva 1, PhD in Medical Sciences, associate professor of the Pediatric dentistry Department
    ORCID ID: 0000-0001-6737-7564
  • V.I. Samokhina 1, PhD in Medical sciences, associate professor of the Dentistry Department
    ORCID ID: 0000-0002-5071-8657
  • A.P. Solonenko 1, PhD in Chemical Sciences, head of Scientific Lab at the Dental Faculty
    ORCID ID: 0000-0003-4967-8464
  • 1 Omsk State Medical University, 644099, Omsk, Russia

Abstract

The aim of the study was to determine the effectiveness of various fluoride-containing drugs on unformed intact enamel and on the focus of demineralization of the enamel of unformed teeth of permanent bite in vivo and in vitro.
Materials and methods.
We studied 30 children aged 6—12 years with both intact permanent teeth with unformed enamel and permanent unformed teeth with foci of enamel demineralization, a total of 110 teeth. For prevention and treatment, the following were used: Group I — fluorine varnish Fluoro-lux (Technodent, Russia), group II — deep fluorination system Gluftored (VladMiVa, Russia), group III — a three—component gel of its own design. Before and after the use of the drugs in vivo, the electrical conductivity of the enamel was measured, in vitro on 45 previously clinically removed permanent teeth, the concentration of calcium in the model solution was measured as an indicator of the degree of solubility of tooth enamel.
Results.
The effectiveness of the tested products depends on the initial state of the enamel and the mechanism of action of the drugs themselves. For the prevention of caries of permanent teeth with unformed enamel, a three-component gel with an optimal content of calcium, phosphorus and fluoride turned out to be the most effective. With regard to the treatment of focal enamel demineralization in unformed teeth, a deep fluorination system is preferable, which allows mechanically sealing the interprism spaces of unformed and demineralized tooth enamel with the formation of a depot of fluoride compounds.
Conclusion.
The stated therapeutic and prophylactic effectiveness of the fluorinated preparations under study was generally confirmed. When prescribing fluoride-containing drugs for the exogenous prevention and treatment of caries in unformed permanent teeth, it is necessary to take into account the degree of hypo- and demineralization of enamel.

Key words:

hypomineralized enamel, demineralization, fluorides, solubility, buffer solution

For Citation

[1]
Skripkina G.I., Matskieva O.V., Samokhina V.I., Solonenko A.P. Clinical and laboratory effectiveness of exogenous prevention and treatment of focal enamel demineralization in children. Clinical Dentistry (Russia).  2024; 27 (2): 22—27. DOI: 10.37988/1811-153X_2024_2_22

References

  1. Kuzmina E.M., Yanushevich O.O., Kuzmina I.N., Lapatina A.V. Tendency in the prevalence of dental caries among the Russian population over a 20-year period. Dental Forum. 2020; 3 (78): 2—8 (In Russian). eLIBRARY ID: 43825063
  2. Samokhina V.I. Epidemiological aspects of the dental health of children 6—12 years old living in a large administrative and economic center of Western Siberia. Pediatric Dentistry and Profilaxis. 2014; 1 (48): 10—13 (In Russian). eLIBRARY ID: 21437702
  3. Skripkina G.I., Garifullina A.Zh., Burnashova T.I. Monitoring of indicators of dental health of schoolchildren of Omsk with the help of European indicators. Pediatric Dentistry and Profilaxis. 2019; 2 (70): 70—75 (In Russian). eLIBRARY ID: 39135640
  4. Makhsumova S.S., Makhsumova I.S., Adylova F.A., Kholmatova Z.D. Problems in modern dental caries prevention in children. Herald of Science and Education. 2021; 13—2 (116): 9—16 (In Russian). eLIBRARY ID: 46653349
  5. Ahovuo-Saloranta A., Forss H., Hiiri A., Nordblad A., Mäkelä M. Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of children and adolescents. Cochrane Database Syst Rev. 2016; 2016 (1): CD003067. PMID: 26780162
  6. Kashbour W., Gupta P., Worthington H.V., Boyers D. Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of children and adolescents. Cochrane Database Syst Rev. 2020; 11 (11): CD003067. PMID: 33142363
  7. Bandeira Lopes L., Machado V., Botelho J., Haubek D. Molar-incisor hypomineralization: an umbrella review. Acta Odontol Scand. 2021; 79 (5): 359—369. PMID: 33524270
  8. Leontiev V.K. Tooth enamel as a biocybernetic system. Moscow: GEOTAR-Media, 2016. Pp. 43—61 (In Russian).
  9. Wu S., Zhang T., Liu Q., Yu X., Zeng X. Effectiveness of fluoride varnish on caries in the first molars of primary schoolchildren: a 3-year longitudinal study in Guangxi Province, China. Int Dent J. 2020; 70 (2): 108—115. PMID: 31705529
  10. Abdellatif E.B., El Kashlan M.K., El Tantawi M. Silver diamine fluoride with sodium fluoride varnish versus silver diamine fluoride in arresting early childhood caries: a 6-months follow up of a randomized field trial. BMC Oral Health. 2023; 23 (1): 875. PMID: 37978488
  11. Smetanin A.A., Ekimov E.V., Skripkina G.I. Ion-exchange processes in the tooth enamel and means of enamel remineralization (the literary review). Pediatric Dentistry and Profilaxis. 2020; 1 (73): 77—80 (In Russian). eLIBRARY ID: 42619545
  12. Burnashova T.I. Regional preventive model of the school dental service: master’s thesis. Perm: Perm State Medical University, 2021. 163 p. (In Russian).
  13. Toumba K.J., Twetman S., Splieth C., Parnell C., van Loveren C., Lygidakis N.Α. Guidelines on the use of fluoride for caries prevention in children: an updated EAPD policy document. Eur Arch Paediatr Dent. 2019; 20 (6): 507—516. PMID: 31631242
  14. Suntsov V.G., Pitaeva A.N., Landinova V.D., Distel› V.A., Garifullina A.Zh., Tordija A.R., Voloshina I.M. Method for obtaining the composition for treating initial dental caries. Patent #2280432, public domain (In Russian).
  15. Leontiev V.K. Fundamental principles of resistance, regulation and pathology of the dental system. Moscow: Mask, 2023. Pp. 70—77 (In Russian).

Downloads

Received

January 11, 2024

Accepted

May 17, 2024

Published on

June 28, 2024