DOI:

10.37988/1811-153X_2024_2_16

Diagnosis and treatment of odontomas in children: literature review and clinical cases

Authors

  • A.G. Uvarova 1, PhD in Medical Sciences, associate professor of the Oral and maxillofacial surgery Department
    ORCID: 0000-0002-9084-0569
  • K.K. Gasparyan 2, dentist, director
    ORCID: 0000-0002-5690-0011
  • F.S. Ayupova 1, PhD in Medical Sciences, associate professor of the Pediatric dentistry, orthodontics and maxillofacial surgery Department
    ORCID: 0000-0002-4194-664X
  • V.V. Volobuev 1, PhD in Medical Sciences, associate professor of the Pediatric dentistry, orthodontics and maxillofacial surgery Department
    ORCID: 0000-0001-9752-6911
  • A.S. Mosesova 1, assistant at the Pediatric dentistry, orthodontics and Maxillofacial surgery Department
    ORCID: 0000-0001-7267-5064
  • V.N. Lovlin 1, PhD in Medical Sciences, assistant professor of the Oral and maxillofacial surgery Department
    ORCID: 0000-0001-6392-2414
  • 1 Kuban State Medical University, 350063, Krasnodar, Russia
  • 2 Dr. Gasparyan Dentistry, 350033, Кrasnodar, Russia

Abstract

Odontoma is classified as benign odontogenic neoplasms. The prevalence according to the literature reaches 25.5—56.1%. Pathology is often asymptomatic, it is detected accidentally during X-ray examination. At the same time, the size and composition of the odontome are variable. This work is devoted to the features of the location, composition, size, most common in clinical practice of odontomas and surgical treatment tactics. The authors studied the cone beam computed tomography and the results of surgical treatment of 12 patients who sought orthodontic care, in whom an odontoma was detected during a routine examination. We selected 3 clinical cases in which the tactics of complex treatment and the outcome of care were determined by the topography and composition of the odontome.
Conclusions.
The most effective method of diagnosis of odontomas today is cone-beam computed tomography. The tactics of surgical treatment are determined by the peculiarities of the location of the odontoma, in particular, relative to the mandibular canal. The possibility of preserving and orthodontic treatment of a retinated permanent tooth depends on the degree of its formation, the tilt of the tooth axis and the preservation of the alveolar bone.

Key words:

odontoma, cone beam computed tomography, surgical treatment, adolescents

For Citation

[1]
Uvarova A.G., Gasparyan K.K., Ayupova F.S., Volobuev V.V., Mosesova A.S., Lovlin V.N. Diagnosis and treatment of odontomas in children: literature review and clinical cases. Clinical Dentistry (Russia).  2024; 27 (2): 16—21. DOI: 10.37988/1811-153X_2024_2_16

References

  1. Sviridov E.G., Kadykova A.I., Redko N.A., Drobyshev A.Yu., Deev R.V. Genetic heterogenety of tumour-like lesions of bones in maxillofacial area. Genes and Cells. 2019; 1: 49—54 (In Russian). eLIBRARY ID: 39695988
  2. da Silva Barros C.C., da Silva L.P., Gonzaga A.K.G., de Medeiros A.M.C., de Souza L.B., da Silveira É.J.D. Neoplasms and non-neoplastic pathologies in the oral and maxillofacial regions in children and adolescents of a Brazilian population. Clin Oral Investig. 2019; 23 (4): 1587—1593. PMID: 30143900
  3. Siriwardena B.S.M.S., Crane H., O›Neill N., Abdelkarim R., Brierley D.J., Franklin C.D., Farthing P.M., Speight P.M., Hunter K.D. Odontogenic tumors and lesions treated in a single specialist oral and maxillofacial pathology unit in the United Kingdom in 1992—2016. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019; 127 (2): 151—166. PMID: 30448231
  4. Bianco B.C.F., Sperandio F.F., Hanemann J.A.C., Pereira A.A.C. New WHO odontogenic tumor classification: impact on prevalence in a population. J Appl Oral Sci. 2020; 28: e20190067. PMID: 31778444
  5. Escobar E., Gómez-Valenzuela F., Peñafiel C., Ortega-Pinto A. Odontogenic tumours in a Chilean population: a retrospective study of 544 cases based on 2022 WHO classification. Med Oral Patol Oral Cir Bucal. 2023; 28 (6): e596-e606. PMID: 37823289
  6. Nagaraj K., Upadhyay M., Yadav S. Impacted maxillary central incisor, canine, and second molar with 2 supernumerary teeth and an odontoma. Am J Orthod Dentofacial Orthop. 2009; 135 (3): 390—9. PMID: 19268839
  7. Onda T., Hayashi K., Katakura A., Takano M. Compound odontoma obstructing the eruption of a mandibular premolar. Oxf Med Case Reports. 2022; 2022 (9): omac102. PMID: 36176953
  8. Mazur M., Di Giorgio G., Ndokaj A., Jedliński M., Corridore D., Marasca B., Salucci A., Polimeni A., Ottolenghi L., Bossù M., Guerra F. Characteristics, diagnosis and treatment of compound odontoma associated with impacted teeth. Children (Basel). 2022; 9 (10): 1509. PMID: 36291445
  9. DeColibus K.A., Rasner D.S., Okhuaihesuyi O., Owosho A.A. Clinicoradiopathologic analysis of odontomas: A retrospective study of 242 cases. Dent J (Basel). 2023; 11 (11): 253. PMID: 37999017
  10. Manfredini M., Ferrario S., Creminelli L., Kuhn E., Poli P.P. Compound odontoma associated with dentigerous cyst incidentally detected in an adult patient: Tomography and histological features. Case Rep Dent. 2022; 2022: 6210289. PMID: 35548385
  11. Preoteasa C.T., Preoteasa E. Compound odontoma — morphology, clinical findings and treatment. Case report. Rom J Morphol Embryol. 2018; 59 (3): 997—1000. PMID: 30534846
  12. Isola G., Cicciù M., Fiorillo L., Matarese G. Association between odontoma and impacted teeth. J Craniofac Surg. 2017; 28 (3): 755—758. PMID: 28468159
  13. Kintarak S., Kumplanont P., Kietthubthew S., Chungpanich S. A nodular mass of the anterior palatal gingiva. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006; 102 (1): 3—6. PMID: 16831665
  14. Soluk Tekkesin M., Pehlivan S., Olgac V., Aksakallı N., Alatli C. Clinical and histopathological investigation of odontomas: review of the literature and presentation of 160 cases. J Oral Maxillofac Surg. 2012; 70 (6): 1358—61. PMID: 21840103
  15. Soluk-Tekkeşin M., Balkan B., Akatay D.K., Atalay B. A rare case of peripheral compound odontoma and review of the literature. Head Neck Pathol. 2022; 16 (3): 913—917. PMID: 35119618
  16. Johnson N.R., Gannon O.M., Savage N.W., Batstone M.D. Frequency of odontogenic cysts and tumors: a systematic review. J Investig Clin Dent. 2014; 5 (1): 9—14. PMID: 23766099
  17. Friedrich R.E., Fuhrmann A., Scheuer H.A., Zustin J. Small peripheral developing odontoma of the maxilla in a 3-year-old patient depicted on cone-beam tomograms. In Vivo. 2010; 24 (6): 895—8. PMID: 21164051
  18. Mikami T., Yagi M., Mizuki H., Takeda Y. Congenital peripheral developing odontoma accompanied by congenital teratomatous fibroma in a 9-month-old boy: a case report. J Oral Sci. 2013; 55 (1): 89—91. PMID: 23485607
  19. Wright J.M., Vered M. Update from the 4th edition of the World Health Organization classification of head and neck tumours: Odontogenic and maxillofacial bone tumors. Head Neck Pathol. 2017; 11 (1): 68—77. PMID: 28247226
  20. Sarradin V., Siegfried A., Uro-Coste E., Delord J.P. [WHO classification of head and neck tumours 2017: Main novelties and update of diagnostic methods]. Bull Cancer. 2018; 105 (6): 596—602 (In French). PMID: 29759330
  21. Slootweg P.J., El-Naggar A.K. World Health Organization 4th edition of head and neck tumor classification: insight into the consequential modifications. Virchows Arch. 2018; 472 (3): 311—313. PMID: 29450648
  22. Soliman N., Al-Khanati N.M., Alkhen M. Rare giant complex composite odontoma of mandible in mixed dentition: Case report with 3-year follow-up and literature review. Ann Med Surg (Lond). 2022; 74: 103355. PMID: 35198177
  23. Silva L.P., Macedo R.A.P., Serpa M.S., Sobral A.P.V., Souza L.B. Global frequency of benign and malignant odontogenic tumors according to the 2005 WHO classification. Journal of Oral Diagnosis. 2017; 2 (1): e20170044. DOI: 10.5935/2525—5711.20170044
  24. Ide F., Mishima K., Saito I., Kusama K. Rare peripheral odontogenic tumors: report of 5 cases and comprehensive review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008; 106 (4): e22—8. PMID: 18718792
  25. de Oliveira M.A., Reis B., Pallos D., Kim Y.J., Braz-Silva P.H., Martins F. The importance of histopathological examination to the final diagnosis of peripheral odontogenic tumors: A case report of a peripheral odontoma. Case Rep Dent. 2019; 2019: 9712816. PMID: 31583140
  26. Hanemann J.A., Oliveira D.T., Garcia N.G., Santos M.R., Pereira A.A. Peripheral compound odontoma erupting in the gingiva. Head Face Med. 2013; 9: 15. PMID: 23758697
  27. Khalifa C., Omami M., Garma M., Slim A., Sioud S., Selmi J. Compound-complex odontoma: A rare case report. Clin Case Rep. 2022; 10 (4): e05658. PMID: 35387291
  28. Nguyen D.K., Van Huynh D. Clinical and radiological characteristics of odontomas: A retrospective study of 90 cases. Imaging Sci Dent. 2023; 53 (2): 117—126. PMID: 37405206

Received

January 25, 2024

Accepted

May 10, 2024

Published on

June 28, 2024