DOI:

10.37988/1811-153X_2023_1_32

The use of non-steroidal anti-inflammatory drugs in dentistry in patients with pathology of the cardiovascular system: a review

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Authors

  • E.N. Anisimova 1, PhD in Medical Sciences, professor of the Pain management in dentistry Department
    ORCID: 0000-0001-7109-6431
  • N.U. Anisimova 1, PhD in Medical Sciences, associate professor of the Pain management in dentistry Department
    ORCID: 0000-0002-3073-7041
  • M.A. Labzenkova 1, assistant at the Pain management in dentistry Department
    ORCID: 0000-0001-5841-4570
  • S.M. Khabib 1, dentist at the Pain management in dentistry Department
    ORCID: 0000-0002-2300-0279
  • 1 Moscow State University of Medicine and Dentistry, 127473, Moscow, Russia

Abstract

The trend towards the prescription of non-steroidal anti-inflammatory drugs in dentistry faces two issues: the choice of the drug by doctors in patients with cardiovascular pathology (including those with a history of myocardial infarction) and the risks of self-prescribing the drug by patients. Objectives: to study the issue of the safe use of non-steroidal anti-inflammatory drugs (NSAIDs) at a dental appointment in patients with cardiovascular pathology, including patients after myocardial infarction. The study presents an analysis of 18 scientific papers on the topic with a consistent comparison of the safety and efficiency of NSAIDs with both opioid analgesics and selective COX-2 inhibitors within the group. >. A comparative analysis of the scientific literature revealed data on the unsafety and, as a result, inappropriate use of opioid analgesics. An effective and safe alternative for patients with cardiovascular pathology are drugs of the NSAID group, which have anti-inflammatory effects and do not cause dependence. In the process of research, it was confirmed that selective COX-2 inhibitors have the lowest cardiotoxicity compared to the non-selective group. The effectiveness of the use of the drug based on nimesulide for the correction of pain at a dental appointment in patients with cardiovascular pathology and a history of myocardial infarction was revealed. >. In patients with cardiovascular pathology, including those with a history of myocardial infarction, to reduce the risks associated with stress due to pain experienced, preventive analgesia and postoperative pain relief with nimesulide-based drugs during dental interventions are recommended. It is imperative to develop guidelines both for dentists on the use of nimesulide in comorbid patients, and for the population about the dangers of self-prescribing drugs.

Key words:

dentistry, analgesics, nimesulide, nonsteroidal anti-inflammatory drugs, cardiovascular system, myocardial infarction

For Citation

[1]
Anisimova E.N., Anisimova N.U., Labzenkova M.A., Khabib S.M. The use of non-steroidal anti-inflammatory drugs in dentistry in patients with pathology of the cardiovascular system: a review. Clinical Dentistry (Russia).  2023; 26 (1): 32—36. DOI: 10.37988/1811-153X_2023_1_32

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Received

January 25, 2023

Accepted

February 5, 2023

Published on

March 22, 2023