DOI:

10.37988/1811-153X_2022_4_64

Peculiarities of selection of modern adhesive medications for treatment of inflammatory periodontal and oral mucosa diseases

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Authors

  • E.V. Velichko 1, PhD in Medical sciences, associate professor of the Dentistry diseases propaedeutics Department
    ORCID: 0000-0002-6196-0422
  • Yu.L. Vasil’ev 2, PhD in Medical Sciences, full professor of Operative surgery and topographic anatomy Department
    ORCID: 0000-0003-3541-6068
  • 1 RUDN University, 117198, Moscow, Russia
  • 2 Sechenov University, 119435, Moscow, Russia

Abstract

On the modern dental market, there is a wide range of adhesive pastes, gels and balms offered for the treatment of diseases of the oral mucosa and periodontium. It is very difficult to choose a suitable remedy, focusing on the trade names of drugs. For the analysis, articles were selected that have been published over the past ten years by Russian and world scientists. The main criteria for the selection of articles were those related to the active ingredients of drugs sold in the Russian Federation and produced in a gel form or in the form of an adhesive balm/paste used for application to the mucous membranes of the oral cavity and gums: Asepta balm for gums adhesive, Asepta gel for gums with propolis, Aftofix, Dentadez active, Dentamed, Donteks, Kamistad, Curasept periodontal gel with chlorhexidine 0.5%, Metrogil Denta, Parodium, Solcoseryl dental adhesive paste, Stomadent ZD, Holisal and Elugel. Based on the properties of the main active substances (anesthetic, non-steroidal anti-inflammatory drug, antiseptic, antibacterial drug), an analysis of their clinical effectiveness was carried out. >. Given the sensitivity of microorganisms of the oral cavity and periodontal pockets, as well as the lack of resistance to the active components of adhesive gels and pastes; the absence of the effect of inactivation of antibiotics and a decrease in the sensitivity of microflora to them; the ability to suppress the activity of the inflammatory process and pain; the possibility of use in environments with sharp shifts in pH, safety and non-toxicity, in case of any violations of the integrity of the mucous membranes (inflammation, neoplastic processes, trauma, radiation, etc.) and periodontium, the drug of choice is the only representative of the combination of cetalkonium chloride and choline salicylate — Holisal gel. This gel should be included in the mandatory treatment protocol for patients with OM and periodontal diseases in order to quickly cope with pain, inflammatory symptoms of diseases and enhance antibacterial and antifungal effects.

Key words:

oral mucosa, periodontium, gels, Holisal, cetalkonium chloride, choline salicylate, benzalkonium chloride, metronidazole, chlorhexidine, resistance

For Citation

[1]
Velichko E.V., Vasil’ev Yu.L. Peculiarities of selection of modern adhesive medications for treatment of inflammatory periodontal and oral mucosa diseases. Clinical Dentistry (Russia).  2022; 25 (4): 64—72. DOI: 10.37988/1811-153X_2022_4_64

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Received

November 7, 2022

Accepted

November 15, 2022

Published on

December 21, 2022