DOI:

10.37988/1811-153X_2022_3_120

Comparative evaluation of the efficiency of different treatment methods of the chronic recurrent aphthous stomatitis

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Authors

  • Z.Z. Khapsirokova 1, assistant at the Therapeutic dentistry Department
    ORCID: 0000-0002-0114-6699
  • A.A. Ponomarev 1, PhD in Medical Sciences, associate professor of the Therapeutic dentistry Department
    ORCID: 0000-0001-9540-9922
  • 1 Belgorod State University, 308015, Belgorod, Russia

Abstract

This paper presents a comparative analysis of the effectiveness of various methods of treatment of patients with chronic recurrent aphthous stomatitis. The aim was to estimate the efficacy of existing methods of treatment of chronic recurrent aphthous stomatitis (CRAS). . We treated 297 patients (168 women and 129 men) aged 18 to 82 years old. All of them were divided into 3 groups depending on treatment method. The I group of 86 patients (40 men and 46 women) were treated by application of antiseptic and anti-inflammatory drugs to the area of aphthous elements. Group II of 89 patients (44 men and 45 women) received treatment of aphthous elements with photoactivated laser FotoSan. In group III, of 122 patients (45 men and 77 women), autoplasma was injected into the area of aphthous rashes as therapy for CRAS. Therapy efficacy was assessed according to three criteria: decrease in pain intensity, complete elimination of pain syndrome and speed of epithelialization of aphthous elements. . A more rapid pain syndrome reduction was observed in the II and III groups, from 4-5 and 8-10 days respectively. The patients in group III had a longer remission period by 12 months and faster healing of aphthous rashes. In Group I, healing was longer than in the previous two and took at least 14-15 days, whereas in Group II from 12-13 days and in Group III from 7-8 days. . The use of the autoplasma in the treatment of recurrent aphthous stomatitis has shown high clinical efficacy which is of great practical interest and requires further investigation.

Key words:

mucosal aphtha, recurrent aphthous stomatitis, autoplasma, FotoSan, treatment

For Citation

[1]
Khapsirokova Z.Z., Ponomarev A.A. Comparative evaluation of the efficiency of different treatment methods of the chronic recurrent aphthous stomatitis. Clinical Dentistry (Russia).  2022; 25 (3): 120—125. DOI: 10.37988/1811-153X_2022_3_120

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Received

June 20, 2022

Accepted

July 25, 2022

Published on

October 30, 2022