DOI:

10.37988/1811-153X_2020_3_19

Recurrent oral aphthae at the patients with acid-dependent diseases of the gastrointestinal tract. Clinical observation

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Authors

  • I.A. Galimova 1, postgraduate at the Therapeutic dentistry Department
  • I.N. Usmanova 1, PhD in Medical Sciences, full professor of the Therapeutic dentistry Department
  • L.P. Gerasimova 1, PhD in Medical Sciences, full professor of the Therapeutic dentistry Department
  • Y. Granot 2, D.M.D., Head of the Hospital Unit of Oral Medicine; senior lecturer of the Faculty of medicine in Galilee
  • A.N. Ishmukhametova 1, PhD in Medical Sciences, associate professor of Internal medicine Departments
  • M.M. Tuigunov 1, PhD in Medical Sciences, full professor of the Microbiology and virology Department
  • R.F. Khusnarizanova 1, PhD in Biology, assistant professor of the Microbiology and virology Department
  • 1 Bashkir State Medical University, 450000, Ufa, Russia
  • 2 Galilee Medical Center, 2210001, Nahariya, Israel

Abstract

The question of the development of recurrent oral aft at the people with acid-dependent diseases of the gastrointestinal tract is insufficiently studied, despite periodic publications in the dental and therapeutic literature. The aim — to study the clinical features of recurrent aft at the patients with acid — dependent diseases of the gastrointestinal tract on the basis of clinical and laboratory research methods. Materials and methods. A comprehensive clinical and dental follow-up of 125 patients aged 25 to 45 years with acid-dependent diseases of the gastrointestinal tract and 58 patients with recurrent aphthas was performed. Results. The typical location of recurrent aft was determined-most often on the mucosa of the upper or lower lip, the mucosa of the lateral surface of the tongue and the mucosa of the cheeks. Identification of some representatives of the normobiom of the oral cavity in the form of the presence of gram-positive and gram-negative facultative anaerobic cocci, sticks and yeast-like fungi of the genus Candida (p≤0.05) allowed to determine the state of dysbiosis, while its more pronounced changes prevail in persons with chronic pancreatitis against the background of hyperacidic gastric secretion. It was found that the pH of the oral fluid in these individuals is within the average values of 5.3—5.6±0.3, and the pH of the gastric juice is within 0.9—1.2±0.5. Conclusion. The results of a comprehensive study suggest a relationship between the development of recurrent oral aft in patients with acid-dependent diseases of the gastrointestinal tract.

Key words:

recurrent aphthae of the oral cavity, normal of the oral cavity, acid-related diseases of the gastrointestinal tract

For Citation

[1]
Galimova I.A., Usmanova I.N., Gerasimova L.P., Granot Y., Ishmukhametova A.N., Tuigunov M.M., Khusnarizanova R.F. Recurrent oral aphthae at the patients with acid-dependent diseases of the gastrointestinal tract. Clinical observation. Clinical Dentistry (Russia).  2020; 3 (95): 19—23. DOI: 10.37988/1811-153X_2020_3_19

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Published on

September 15, 2020