DOI:

10.37988/1811-153X_2024_4_70

Microbiologic rationale for the use of antibacterial collagen plates in dental prosthetics of patients with diabetes mellitus

Downloads

Authors

  • E.A. Bulycheva 1, 2, Doctor of Science in Medicine, professor and head of the Department of additional education in dentistry specialties; professor of the Prosthodontics, materials science and orthodontics Department
    ORCID: 0000-0002-1175-5682
  • N.A. Shevkunova 3, PhD in Medical Sciences, associate professor of the Prosthetic dentistry Department
    ORCID: 0000-0002-2540-3311
  • V.N. Trezubov 2, Doctor of Science in Medicine, full professor of the Prosthodontics, materials science and orthodontics Department
    ORCID: 0000-0003-0532-5632
  • G.S. Arkhipov 1, Doctor of Science in Medicine, full professor of the Microbiology, immunology and infectious diseases Department
  • Yu.V. Alpatyeva 1, 2, PhD in Medical Sciences, associate professor of the Department of additional education in dentistry specialties; assistant professor of the Prosthodontics, materials science and orthodontics Department
    ORCID: 0000-0001-7112-2310
  • I.A. Butyugin 1, 4, PhD in Medical Sciences, associate professor of the Department of additional education in dentistry specialties; associate professor of the Clinical dentistry Department
    ORCID: 0009-0006-4555-5570
  • N.N. Nikitina 1, senior lecturer of the Microbiology, immunology and infectious diseases Department
    ORCID: 0000-0001-8766-6822
  • 1 Yaroslav-the-Wise Novgorod State University, 173003, Veliky Novgorod, Russia
  • 2 Pavlov University, 197101, Saint-Petersburg, Russia
  • 3 Izhevsk State Medical Academy, 426034, Izhevsk, Russia
  • 4 Saint-Petersburg Medico-Social Institute, 195271, Saint-Petersburg, Russia

Abstract

The article presents changes in oral cavity parameters of patients with diabetes mellitus and partial removable dentures during treatment with collagen plates. The results of the study showed that when using removable dentures, pain sensitivity in diabetic patients occurred 3.6 times, and inflammation was diagnosed 2.4 times more often than in those who remained healthy (p<0.001). This led to the need not only to correct prostheses but also to the use of drugs that reduce inflammation and pain. The use of collagen plates containing plant medicinal substances had a positive effect on the dynamics of the inflammatory process in the tissues of the prosthetic bed and was confirmed by a pronounced antimicrobial effect on pathogenic Staphylococci, Escherichia coli, and Candida.

Key words:

oral microflora, diabetes mellitus, decompensated dentition, collagen

For Citation

[1]
Bulycheva E.A., Shevkunova N.A., Trezubov V.N., Arkhipov G.S., Alpatyeva Yu.V., Butyugin I.A., Nikitina N.N. Microbiologic rationale for the use of antibacterial collagen plates in dental prosthetics of patients with diabetes mellitus. Clinical Dentistry (Russia).  2024; 27 (4): 70—74. DOI: 10.37988/1811-153X_2024_4_70

References

  1. Naumova V.N., Maslak E.E. Diabetes mellitus and dental health: problems in diagnosis and treatment of dental clinics’ patients. Practical medicine. 2013; 4 (72): 10—14 (In Russian). eLIBRARY ID: 20377831
  2. Khan S.Q., Khabeer A., Al-Thobity A.M., Benrashed M.A., Alyousef N.I., AlMaimouni Y. Correlation between diabetes mellitus and number of restored, carious lesions and missing teeth: A retrospective radiographic evaluation. Saudi Dent J. 2021; 33 (3): 131—136. PMID: 33679105
  3. Ahmad R., Haque M. Oral health messiers: Diabetes mellitus relevance. Diabetes Metab Syndr Obes. 2021; 14: 3001—3015. PMID: 34234496
  4. Negrato C.A., Tarzia O. Buccal alterations in diabetes mellitus. Diabetol Metab Syndr. 2010; 2: 3. PMID: 20180965
  5. Genco R.J., Borgnakke W.S. Diabetes as a potential risk for periodontitis: association studies. Periodontol 2000. 2020; 83 (1): 40—45. PMID: 32385881
  6. Bulycheva E., Trezubov V., Spitsyna O., Bystrova Y., Alpatyeva Y., Bulycheva D. Criteria for assessing the quality of treatment of disorders of the masticatory and speech apparatus. Sovremennaya stomatologiya (Belarus). 2020; 4 (81): 87—90 (In Russian). eLIBRARY ID: 44597955
  7. Trezubov V.N., Rozov R.A. Decompensated (compromised) dentition (philosophical essay). Parodontologiya. 2020; 2: 134—139 (In Russian). eLIBRARY ID: 42820283
  8. Polushkina N.A., Vecherkina Zh.V., Primacheva N.V., Smolina A.A. Evaluation of orthopedic treatment with removable dentures in patients with periodontal pathology on the background of diabetes mellitus. Journal of New Medical Technologies, EEdition. 2022; 1: 25—30 (In Russian). eLIBRARY ID: 48052333
  9. Silina E.V., Stupin V.A., Gabitov R.B. Collagen role in the mechanisms of chronic wounds healing diabetic foot syndrome. Clinical Medicine (Russian Journal). 2018; 2: 106—115 (In Russian). eLIBRARY ID: 32837331
  10. Yang S., Li Y., Liu C., Wu Y., Wan Z., Shen D. Pathogenesis and treatment of wound healing in patients with diabetes after tooth extraction. Front Endocrinol (Lausanne). 2022; 13: 949535. PMID: 36213270
  11. Radović K., Brković B., Roganović J., Ilić J., Milić Lemić A., Jovanović B. Salivary VEGF and post-extraction wound healing in type 2 diabetic immediate denture wearers. Acta Odontol Scand. 2022; 80 (1): 9—14. PMID: 34033524
  12. Spampinato S.F., Caruso G.I., De Pasquale R., Sortino M.A., Merlo S. The treatment of impaired wound healing in diabetes: Looking among old drugs. Pharmaceuticals (Basel). 2020; 13 (4): 60. PMID: 32244718
  13. Picke A.K., Campbell G., Napoli N., Hofbauer L.C., Rauner M. Update on the impact of type 2 diabetes mellitus on bone metabolism and material properties. Endocr Connect. 2019; 8 (3): R55-R70. PMID: 30772871
  14. Shevkunova N.A., Vorobyov M.V., Gushchin V.V. The use of collagen plates in orthopedic dental rehabilitation of patients with drug-compensated diabetes mellitus. Farmateka. 2021; 4: 51—54 (In Russian). eLIBRARY ID: 45488998

Downloads

Received

May 22, 2024

Accepted

November 5, 2024

Published on

December 17, 2024