DOI:

10.37988/1811-153X_2024_2_22

Clinical and laboratory effectiveness of exogenous prevention and treatment of focal enamel demineralization in children

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Authors

  • G.I. Skripkina 1, PhD in Medical Sciences, associate professor and head of the Pediatric dentistry Department
    ORCID: 0000-0001-7783-6111
  • O.V. Matskieva 1, PhD in Medical Sciences, associate professor of the Pediatric dentistry Department
    ORCID: 0000-0001-6737-7564
  • V.I. Samokhina 1, PhD in Medical sciences, associate professor of the Dentistry Department
    ORCID: 0000-0002-5071-8657
  • A.P. Solonenko 1, PhD in Chemical Sciences, head of Scientific Lab at the Dental Faculty
    ORCID: 0000-0003-4967-8464
  • 1 Omsk State Medical University, 644099, Omsk, Russia

Abstract

The aim of the study was to determine the effectiveness of various fluoride-containing drugs on unformed intact enamel and on the focus of demineralization of the enamel of unformed teeth of permanent bite in vivo and in vitro.
Materials and methods.
We studied 30 children aged 6—12 years with both intact permanent teeth with unformed enamel and permanent unformed teeth with foci of enamel demineralization, a total of 110 teeth. For prevention and treatment, the following were used: Group I — fluorine varnish Fluoro-lux (Technodent, Russia), group II — deep fluorination system Gluftored (VladMiVa, Russia), group III — a three—component gel of its own design. Before and after the use of the drugs in vivo, the electrical conductivity of the enamel was measured, in vitro on 45 previously clinically removed permanent teeth, the concentration of calcium in the model solution was measured as an indicator of the degree of solubility of tooth enamel.
Results.
The effectiveness of the tested products depends on the initial state of the enamel and the mechanism of action of the drugs themselves. For the prevention of caries of permanent teeth with unformed enamel, a three-component gel with an optimal content of calcium, phosphorus and fluoride turned out to be the most effective. With regard to the treatment of focal enamel demineralization in unformed teeth, a deep fluorination system is preferable, which allows mechanically sealing the interprism spaces of unformed and demineralized tooth enamel with the formation of a depot of fluoride compounds.
Conclusion.
The stated therapeutic and prophylactic effectiveness of the fluorinated preparations under study was generally confirmed. When prescribing fluoride-containing drugs for the exogenous prevention and treatment of caries in unformed permanent teeth, it is necessary to take into account the degree of hypo- and demineralization of enamel.

Key words:

hypomineralized enamel, demineralization, fluorides, solubility, buffer solution

For Citation

[1]
Skripkina G.I., Matskieva O.V., Samokhina V.I., Solonenko A.P. Clinical and laboratory effectiveness of exogenous prevention and treatment of focal enamel demineralization in children. Clinical Dentistry (Russia).  2024; 27 (2): 22—27. DOI: 10.37988/1811-153X_2024_2_22

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Received

January 11, 2024

Accepted

May 17, 2024

Published on

June 28, 2024