DOI:

10.37988/1811-153X_2023_2_44

Structural-morphological interrelation of the microcirculatory bed of the perioostus of the jaws in chronic generalized periodontitis in the experiment

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Authors

  • Z.K. Shamanova 1, postgraduate at the General dentistry Department
    ORCID: 0009-0009-8330-9364
  • A.V. Arutyunov 1, PhD in Medical Sciences, associate professor and head of General dentistry Department
    ORCID: 0000-0001-8823-1409
  • Yu.V. Verevkina 1, postgraduate at the General dentistry Department
    ORCID: 0000-0003-3948-6960
  • S.V. Sirak 2, PhD in Medical Sciences, full professor of the Dentistry Department
    ORCID: 0000-0002-4924-5792
  • N.I. Bykova 1, PhD in Medical Sciences, associate professor of the Pediatric dentistry, orthodontics and maxillofacial surgery Department
    ORCID: 0000-0002-0573-7242
  • T.L. Kobylkina 2, PhD in Medical Sciences, associate professor of the Dentistry Department
    ORCID: 0000-0003-1189-0136
  • 1 Kuban State Medical University, 350063, Krasnodar, Russia
  • 2 Stavropol State Medical University, 355017, Stavropol, Russia

Abstract

Effective therapy of chronic generalized periodontitis is impossible without understanding the relationship of the elements of the periodontal tissue complex with the microvascular bed of the periodontal, periosteum, alveolar bone of the jaw. The literature data on the main sources of bone and periosteum vascularization in chronic generalized periodontitis, accompanied by resorption and atrophy of the alveolar bone, are quite contradictory, which justifies the relevance of the study of structural and morphological elements of the microcirculatory bed of the periosteum of the alveolar bone of the jaw with chronic generalized periodontitis artificially modeled on experimental animals. Objectives: determination of structural and morphological elements of the microcirculatory bed of the periosteum of the alveolar bone of the jaw in chronic generalized periodontitis.
Materials and methods.
The experimental animal study included 50 rabbits of the Gray Giant breed, which were divided into 3 groups: the intact, the control and the main. In the control group and in the main group of animals after modeling chronic generalized periodontitis treatment was the same, but in the main group was prescribed an additional set of therapy.
Results.
In the control group in the periosteum of the jaws were detected pseudoinvolutive changes in the terminal bloodstream, which consist in a decrease in the number of microcapillaries per unit area, increased tortuosity of venules, the appearance of varicose veins in them, which indicates a decrease in the intensity of metabolic processes and a tendency to stagnation of blood. In the preparations of the main group in similar dental alveolar segments, an increase in the number of microcapillaries with an increase in the diffusion surface of the studied vessels was found, which confirms the hypothesis of a high adaptogenic ability of the microvascular bed to increase blood outflow in conditions of inflammation in the periodontal: on average, 72.9±2.24 capillaries per 1 mm2 of the periosteum in the control group, and their diffusion surface was equal to 0.35±0.09 mm2. In the main group the capillary surface for one dental alveolar segment was 4.62 mm2, which is significantly comparable with the indicators of the intact group of animals (p<0.05), amounting to 66.8% the diffusion surface of all the vessels studied, with an average of 88.6±4.08 capillaries per 1 mm2 of the periosteum in the main group, and their diffusion surface was equal to 0.86±0.11 mm2.
Conclusions.
The obtained data about morphofunctional changes in the microcirculatory bed of the periosteum can be used to evaluate the effectiveness of therapy in the treatment of chronic generalized periodontitis.

Key words:

periodontitis, jaw, periosteum, inflammation, microcirculation, experiment

For Citation

[1]
Shamanova Z.K., Arutyunov A.V., Verevkina Yu.V., Sirak S.V., Bykova N.I., Kobylkina T.L. Structural-morphological interrelation of the microcirculatory bed of the perioostus of the jaws in chronic generalized periodontitis in the experiment. Clinical Dentistry (Russia).  2023; 26 (2): 44—51. DOI: 10.37988/1811-153X_2023_2_44

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Received

March 26, 2023

Accepted

June 7, 2023

Published on

July 6, 2023