The effectiveness of the use toothpaste R.O.C.S. PRO Moisturizing in patients with xerostomia

Abstract

Creating a comfortable conditions of the oral mucosa and quality of life in patients with xerostomia is an urgent problem both for clinicians, who constantly note this symptom in many patients, and for manufacturers and suppliers of oral hygiene products. Patients with a symptom of «dry mouth», in addition to symptomatic replacement therapy with artificial analogues of saliva, need to optimize individual hygiene, because a violation of the qualitative or quantitative level of saliva will inevitably lead to a deterioration in the oral tissues. Therefore, the development of domestic oral hygiene products that reduce the severity of xerostomia manifestations and are economically affordable is of great importance in improving the quality of life of patients with dry mouth. This study presents the results of a study of a number of laboratory and consumer properties of R.O.C.S. PRO Moisturizing toothpaste for patients with xerostomia of varying severity. To assess the oral cavity condition before testing the paste, a clinical examination of 43 people (4 men and 39 women) aged 23 to 67 years was carried out. Participants were followed up twice: 1 and 4 weeks after the start of moisturizing toothpaste. According to pH-metry, after the using of this paste, there is a pronounced shift in the pH to the alkaline side, which is explained by the presence of a buffer system in the composition of the paste, which can neutralize the excess acidity of the oral fluid. An increase in the volume of salivation according to sialometry over the period of application of the paste (by an average of 0.6 ml) may be due to the presence of a natural mint salivary stimulating fragrance in the composition of the paste. Analysis of the results of the pH-metry study, showed acidification of the oral fluid compared to the generally accepted pH standard with a decrease in the volume of saliva in the oral cavity. The lowest pH in the observed patients was 4.7, with an intragroup average of 5.6. The evaluation of the pH-metry data of the oral fluid in dynamics against the background of the use of the paste showed the presence of a shift in its reaction to the alkaline side. Observation during the month revealed a gradual restoration of acid-base balance in the oral cavity, although there was no return to pH in the range of 6.8-7.4. The obtained results of positive dynamic changes in metabolic processes in the oral fluid against the background of the use of the developed paste give grounds for its broad recommendation in order to normalize the state of the oral mucosa and mineral metabolism in the enamel in patients with symptoms of xerostomia in a shorter time.