DOI:

10.37988/1811-153X_2020_3_61

The stability coefficient of dental implants and its relationship with biomarkers of bone metabolism

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Authors

  • T.G. Mahmudov 1, PhD in Medical sciences, doctoral candidate of the Prosthodontics department
  • 1 Azerbaijan Medical University, AZ1012, Baku, Azerbaijan

Abstract

Achieving and maintaining implant stability are prerequisites for a successful clinical outcome. It is important to measure implant stability (ISQ) and further study of alkaline phosphatase (ALP) and osteocalcin as indicators of the activity of reparative processes. Objectives: to measurement of ISQ during the healing period using the method of resonance frequency analysis (RFA) and the study of the relationship between ISQ values with markers of bone formation. Materials and methods. Dental intraosseous implantation was performed in 67 patients, the average age was 51.8±3.08 years. 98 screw intraosseous implants of the MIS (Medical Implant System) system were installed. The implant survival was determined according to the Boozer criteria, plaque and bleeding indices. Applied RFA apparatus “Osstell ISQ”. In the oral fluid, alkaline phosphatase and osteocalcin are determined. The measurements were carried out immediately after installation, after 14 days and 3 and 6 months. The Pearson correlation coefficient was calculated. Results. The average scores for the Silness—Loe and Mulleman—Cowell indices were 0.79±0.28 and 0.50±0.30, respectively. After 14 days, the ISQ value compared to the initial one decreased by 2.14%. After 3 months, the ISQ increased by 11.7% compared with the initial one and by 12.93% compared with the value noted after 14 days. After 6 months, the ISQ exceeded the initial value by 12.70%. The activity of ALP immediately after treatment and after 14 days did not differ. After 3 and 6 months, the activity of ALP in comparison with the initial value increased by an average of 2.9%, respectively. The maximum value of osteocalcin was noted after 14 days, after 3 and 6 months it slightly decreased. Immediately after treatment, the correlation coefficient between alkaline phosphatase and osteocalcin was +0.375, after 14 days — +0.351, after 3 and 6 months — +0.304 and +0.141 (p=0.23) respectively. A very weak correlation of ISQ with biomarkers was noted. Conclusion. ISQ values showed high implant stability. Successful integration of implants was confirmed by changes in ALP and osteocalcin concentrations, the positive dynamics of which indicated positive mineralization and repair. During the healing period, ISQ values were weakly correlated with ALP and osteocalcin. This study confirms the importance of monitoring ISQ values and markers of bone metabolism during dental implantation.

Key words:

dental implants, resonant frequency analysis, stability coefficient, alkaline phosphatase, osteocalcin, oral fluid, correlation

For Citation

[1]
Mahmudov T.G. The stability coefficient of dental implants and its relationship with biomarkers of bone metabolism. Clinical Dentistry (Russia).  2020; 3 (95): 61—65. DOI: 10.37988/1811-153X_2020_3_61

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Published on

September 15, 2020