DOI:
10.37988/1811-153X_2020_1_12The combined use of herbal remedies in patients with chronic periodontitis: experimental and applied aspects
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Abstract
Inflammatory and destructive periodontal diseases are one of the most complex and common forms of pathology and the main cause of tooth loss among the adult population, therefore, the development and implementation of new dosage forms for the treatment of inflammatory periodontal diseases is an urgent task. The herbal medicines used have a variety of pharmacological properties that can be useful as antimicrobial effects on biofilms or as immunostimulating drugs. The aim of the work was to substantiate the effectiveness of the herbal preparations Tonsinal and phytoplastin TsM-1 according to the results of clinical and laboratory studies in the in vitro bioreactor and in the local treatment of periodontitis. The obtained results contributed to confirming the effectiveness of the integrated use of herbal preparations with the aim of prolonging the remission of the disease, as well as improving the quality of periodontal care.
Key words:
periodontitis, herbal medicine, bioreactor, biofilm, periodontopathogenic microfloraFor Citation
References
- Sanz M., Beighton D., Curtis M.A., Cury J.A., Dige I., Dommisch H., Ellwood R., Giacaman R.A., Herrera D., Herzberg M.C., Könönen E., Marsh P.D., Meyle J., Mira A., Molina A., Mombelli A., Quirynen M., Reynolds E.C., Shapira L., Zaura E. Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease. — J Clin Periodontol. — 2017; 44 (suppl. 18): S5—S11.
- Tsarev V.N. Microbiology, virology, immunology. 2nd edition. — Moscow: GEOTAR-Media, 2019: 129—140 (In Russ.).
- Bosshardt D.D., Lang N.P. The junctional epithelium: from health to disease. — J Dent Res. — 2005; 84 (1): 9—20.
- Lang N.P., Schätzle M.A., Löe H. Gingivitis as a risk factor in periodontal disease. — J Clin Periodontol. — 2009; 36 (suppl. 10): 3—8.
- Reynolds M.A., Kao R.T., Camargo P.M., Caton J.G., Clem D.S., Fiorellini J.P., Geisinger M.L., Mills M.P., Nares S., Nevins M.L. Periodontal regeneration — intrabony defects: a consensus report from the AAP Regeneration Workshop. — J Periodontol. — 2015; 86 (2 Suppl): S105—7.
- Orekhova L.Yu., Atrushkevich V.G., Mikhal’chenko D.V., Gorbacheva I.A., Lapina N.V. Dental health and polymorbidity: analysis of modern approaches to the treatment of dental diseases. — Periodontology. — 2017; 3 (84): 15—7 (In Russ.).
- Chergeshtov Yu.I., Manuylov B.M., Romashchenko V.V., Luzina V.V., Afanas’eva E.A., Drobyshev A.Yu. A complex method of surgical treatment using innovative herbal remedies in patients with chronic odontogenic maxillary sinusitis caused by errors in endodontic treatment. — Endodontology Today. — 2015; 3: 7—12 (In Russ.).
- Kassebaum N.J., Bernabé E., Dahiya M., Bhandari B., Murray C.J., Marcenes W. Global burden of severe periodontitis in 1990—2010: a systematic review and meta-regression. — J Dent Res. — 2014; 93 (11): 1045—53.
- Morand D.N., Davideau J.L., Clauss F., Jessel N., Tenenbaum H., Huck O. Cytokines during periodontal wound healing: potential application for new therapeutic approach. — Oral Dis. — 2017; 23 (3): 300—11.
- Haffajee A.D., Teles R.P., Socransky S.S. The effect of periodontal therapy on the composition of the subgingival microbiota. — Periodontol 2000. — 2006; 42: 219—58.
- Tsarev V.N., Labazanov A.A., Ippolitov E.V., Shulakov V.V., Pashkov E.P. The problem of resistance of causative agents of odontogenic infection to antibiotics and the development of an express method for identifying resistant strains. — Clinical Dentistry. — 2016; 3 (79): 26—31 (In Russ.).
- Yanushevich O.O., Akhmedov G.D., Panin A.M., Arutyunov S.D., Tsarev V.N. Microecology of the oral cavity and infectious and inflammatory complications in surgical dentistry. — Moscow: Practical medicine, 2019: 125—136 (In Russ.).