Влияние двух ополаскивателей с хлоргексидином на развитие зубной бляшки, гингивита и дисколорита. Рандомизированное слепое плацебо-контролируемое исследование

Авторы

  • К. Лоренц 1, медицинский факультет, отделение консервативной стоматологии
  • Г. Брун 1, медицинский факультет, отделение консервативной стоматологии
  • С. Хойманн 2, отделение статистики
  • Л. Нетушил 1, медицинский факультет, отделение консервативной стоматологии
  • М. Брекс , Частная практика, Брюссель, Бельгия
  • Т. Гофман , Частная практика, Брюссель, Бельгия
  • 1 Дрезденский технический университет, Германия
  • 2 Мюнхенский университет, Германия

Аннотация

Не было найдено никакой разницы в эффективности между двумя составами с хлоргексидином и положительным контролем. На 21-й день наблюдалось статистически значимое снижение воспаления десен и накопления зубного налета по сравнению с плацебо. Никаких отрицательных эффектов, кроме дисколорита и вкусовых нарушений, зафиксировано не было. Два ополаскивателя для рта с хлоргексидином были способны подавлять повторный рост зубного налета и воспаление десны. Ни отсутствие в растворе хлоргексидина спирта, ни добавление фторида натрия не ослабили клиническую эффективность хлоргексидина относительно анализируемых клинических параметров.

Ключевые слова:

рандомизированное слепое плацебо-контролируемое исследование, гингивит

Для цитирования

[1]
Лоренц К., Брун Г., Хойманн С., Нетушил Л., Брекс М., Гофман Т. Влияние двух ополаскивателей с хлоргексидином на развитие зубной бляшки, гингивита и дисколорита. Рандомизированное слепое плацебо-контролируемое исследование. — Клиническая стоматология. — 2015; 4 (76): 74-81

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Опубликовано

01.12.2015