DOI:

10.37988/1811-153X_2023_1_37

Current views on denticle etiology and pathogenesis (a review)

Authors

  • 1 Pavlov University, 197022, Saint-Petersburg, Russia

Abstract

In the modern world, despite the achievements of domestic therapeutic dentistry, denticles continue to cause difficulties in endodontic treatment. At the same time, the available literature contains insufficient information about the etiology, pathogenesis, as well as approaches to diagnosis and treatment options for this type of pathology. The aim of the study: Is to analyze scientific publications on the etiology, pathogenesis, features of the histological structure, morphology, chemical composition, classification and prevalence of denticles, as well as their relationship with general somatic pathology. The study of various scientific sources made it possible to conclude that denticles are multifactorial as an isolated and combined pathology of the dental pulp. Their occurrence can be influenced by teeth abrasion, hereditary disorders in the hard tissues formation, as well as pathological processes within teeth and surrounding tissues. In addition, the role of age as an etiological factor in the development of calcifications in the dental cavity is important, since the synthetic properties of odontoblasts change with age and the intensity of sclerotic processes in the pulp tissues increases. The multifactorial nature of this pathology correlates with the pathogenetic mechanisms of its occurrence, which are covered in the literature from different perspectives. Denticles can occur as a result of degenerative changes in the pulp, significant role is played by the phenomenon of excessive formation of odontoblasts from preodontoblasts. The microbiological mechanism of the pathogenesis of denticles (Nanobacterium Sanguineum) is also considered. The mechanical load acting on the teeth during orthodontic treatment can also play an important role in the formation of petrificates. >. Taking into consideration the great complexity that denticles create during endodontic treatment, a detailed analysis and study of their etiology and mechanisms of occurrence are of great interest to modern practical dentistry.

Key words:

denticles, calcifications, calculus pulpitis, pulp petrification, etiology, pathogenesis

For Citation

[1]
Osipova V.A., Kolyada A.A., Molokova V.A. Current views on denticle etiology and pathogenesis (a review). Clinical Dentistry (Russia).  2023; 26 (1): 37—45. DOI: 10.37988/1811-153X_2023_1_37

References

  1. Aleynikov S.A., Maksimovskiy Yu.M., Grinin V.M. The effectiveness of endodontic re-treatment of teeth after filling the roots with the most-used pasts. Endodontics Today. 2008; 2: 67—72 (In Russ.). eLIBRARY ID: 11586774
  2. Arutyunov S.D., Dihanova V.G., Kitsul I.S. Technical approaches to estimation of quality of treatment of root channels of teeth from a position of choice and observance of medical technologies. Siberian medical journal (Irkutsk). 2011; 2: 104—106 (In Russ.). eLIBRARY ID: 16394864
  3. Goga R., Chandler N.P., Oginni A.O. Pulp stones: a review. Int Endod J. 2008; 41 (6): 457—68. PMID: 18422587
  4. Bykov V.L. Histology and embryonic development of the organs of the human oral cavity. St. Petersburg: Spec. lit., 2014. Pp. 228—230 (In Russ.). http://kstom.ru
  5. Afanasiev Yu.I., Yurina N.A., Vinnikov Ya.A., Radostina A.I., Chentsov Yu.S. Histology, embryology and cytology. Moscow: GEOTAR-Media, 2014. Pp. 503—505 (In Russ.).
  6. Luzhkova E.L. Inflammation of the pulp. Etiology, pathogenesis, classification. In: Proceedings of the XXXIII International Scientific Conference “Young academics research”. Kazan, 2022. Pp. 15—22 (In Russ.). eLIBRARY ID: 48451169
  7. Chen G., Huang L.G., Yeh P.C. Detecting calcified pulp stones in patients with periodontal diseases using digital panoramic and periapical radiographies. J Dent Sci. 2022; 17 (2): 965—972. PMID: 35756760
  8. Rukavishnikova L.I. Calcifications in the tooth pulp and their effect on endodontic treatment. 2011: 1—7 (In Russ.). eLIBRARY ID: 23367920
  9. Kiseleva D.V., Shagalov E.S., Zaitseva M.V., Pankrushina E.A., Joints S.G., Spivak N. Physico-chemical characteristics of pathogenic calcifications of dental pulp. Ekaterinburg, 2018. Pp. 90—93 (In Russ.). eLIBRARY ID: 34903251
  10. Mitronin A., Burda A., Emeldyazhev I., Islamova E., Shumsky A., Supilnikov A., Volova L. The degree of calcification of the pulp of the tooth mineralization and the choice of tactics of endodontic treatment. Cathedra. Dental education. 2016; 55: 21—22 (In Russ.). eLIBRARY ID: 27495263
  11. Burguera J.L., Burguera M. Recent on-line processing procedures for biological samples for determination of trace elements by atomic spectrometric methods. Spectrochimica Acta Part B. 2009; 64 (6): 451—458. DOI: 10.1016/j.sab.2009.01.004
  12. Berès F., Isaac J., Mouton L., Rouzière S., Berdal A., Simon S., Dessombz A. Comparative Physicochemical Analysis of Pulp Stone and Dentin. J Endod. 2016; 42 (3): 432—8. PMID: 26794341
  13. Kutsevlyak V.F., Gorgol N.I., Bobrovska N.P. Morphological changes in the dentin of the teeth of rats in conditions of high lead content. Bulletin of Dentistry. 2015; 1 (90): 32—35 (In Russ.). eLIBRARY ID: 25933506
  14. Palatyńska-Ulatowska A., Fernandes M.C., Pietrzycka K., Koprowicz A., Klimek L., Souza R.A., Pradebon M., de Figueiredo J.A.P. The pulp stones: Morphological analysis in scanning electron microscopy and spectroscopic chemical quantification. Medicina (Kaunas). 2021; 58 (1): 5. PMID: 35056314
  15. Grigoriev S.S., Saypeev K.A. Increased abrasion of hard dental tissues. Review. Ural Medical Journal. 2014; 5 (119): 16—20 (In Russ.). eLIBRARY ID: 21982437
  16. Normurodova R.Z., Dadabaeva M.U., Mirkhoshimova M.F., Babakhanov R.G., Rakhmanova M.D. Substantiation of dental status in patients suffering from diabetes mellitus in a hospital setting. Modern science: problems, ideas, trends. 2021: 358—366 (In Russ.). eLIBRARY ID: 44783881
  17. Kamilevich A.A. Clinical features and structure of the microbiota of periodontal tissues in young people: master's thesis. Kazan, 2019. Pp. 50—51 (In Russ.). eLIBRARY ID: 46184854
  18. Nozu A., Hamano S., Tomokiyo A., Hasegawa D., Sugii H., Yoshida S., Mitarai H., Taniguchi S., Wada N., Maeda H. Senescence and odontoblastic differentiation of dental pulp cells. J Cell Physiol. 2018; 234 (1): 849—859. PMID: 30078208
  19. Kumar C., Bagga M., Mohan V., Raghav N. An overview on clinical implications of nanobacteria. Indian Academy of Oral Medicine and Radiology. 2011; 23 (5): 354—359.
  20. Frolov A.O., Popov S.A., Artushenko N.K., Shalak O.V. Doppler ultrasound pulp diagnosis of teeth intruded with temporary anchorage devices. The Dental Institute. 2017; 1 (74): 64—66 (In Russ.). eLIBRARY ID: 28965089
  21. George J., David R.M., Thomas P., Bindhu P.R., Pillai R.K. Radiographic assessment of pulp stones: a retrospective study. International Journal of Current Research. 2018; 10 (9): 73837—73841.
  22. Sübay R.K., Kaya H., Tarim B., Sübay A., Cox C.F. Response of human pulpal tissue to orthodontic extrusive applications. J Endod. 2001; 27 (8): 508—11. PMID: 11501587
  23. Ravichandran S., Vadivel J.K. Prevalence of pulp stones in IOPA radiographs. J Adv Pharm Technol Res. 2022; 13 (Suppl 1): S63-S66. PMID: 36643118
  24. Babu S.J., Swarnalatha C., Rao A.P., Kumar B.B., Tilak B.P., Naidu R.B., Nayyar A.S. Pulp stones as risk predictors for coronary artery disease. Int J Prev Med. 2020; 11: 7. PMID: 32089807
  25. Ertas E.T,, Inci M., Demirtas A., Ertas H., Yengil E., Sisman Y., Gokce C. A radiographic correlation between renal and pulp stones. West Indian Med J. 2014; 63 (6): 620—5. PMID: 25803378
  26. Elyas M.A., Al Obaid H.H., Aljumaah N.S., Alqahtani M.W., Aljafar A.A., Alhasher K.H., Alqarni M.F., Alzahib H.A., Alyousef S.N., Alqarni M.K., Zuhair F. A.. Pulp stones and its relation with co-morbid diseases. International Journal of Community Medicine and Public Health. 2023; 10 (2): 883—6. DOI: 10.18203/2394-6040.ijcmph20230018
  27. Movahhedian N., Haghnegahdar A., Owji F. How the prevalence of pulp stone in a population predicts the risk for kidney stone. Iran Endod J. 2018; 13 (2): 246—250. PMID: 29707023
  28. Boyce A.M., Lee A.E., Roszko K.L., Gafni R.I. Hyperphosphatemic tumoral calcinosis: Pathogenesis, clinical presentation, and challenges in management. Front Endocrinol (Lausanne). 2020; 11: 293. PMID: 32457699
  29. Perlea P., Dragomir C., Bodeanu A., Temelcea A.N., Iliescu A.A. A rare case diagnosed as dentin dysplasia type II. Rom J Morphol Embryol. 2018; 59 (1): 359—365. PMID: 29940650
  30. Marik I., Marikova A., Hyankova E., Kozlowski K. Familial expansile osteolysis—not exclusively an adult disorder. Skeletal Radiol. 2006; 35 (11): 872—5. PMID: 16470392
  31. Sarode G.S., Sarode S.C., Anand R., Waknis P. True pulp stones in compound odontome: an unusual finding. World Journal of Dentistry. 2015; 6 (4): 241—242. DOI: 10.5005/jp-journals-10015-1352
  32. Satheeshkumar P.S., Mohan M.P., Saji S., Sadanandan S., George G. Idiopathic dental pulp calcifications in a tertiary care setting in South India. J Conserv Dent. 2013; 16 (1): 50—5. PMID: 23349577
  33. Marwaha M., Chopra R., Chaudhuri P., Gupta A., Sachdev J. Multiple pulp stones in primary and developing permanent dentition: a report of 4 cases. Case Rep Dent. 2012; 2012: 408045. PMID: 22970392
  34. Edds A.C., Walden J.E., Scheetz J.P., Goldsmith L.J., Drisko C.L., Eleazer P.D. Pilot study of correlation of pulp stones with cardiovascular disease. J Endod. 2005; 31 (7): 504—6. PMID: 15980708
  35. Swathy S., Sukumaran G., Varsha S.L. Prevalence of pulp stones in patients with history of cardiac diseases. Research Journal of Pharmacy and Technology. 2015; 8 (12): 1625—1628. DOI: 10.5958/0974-360X.2015.00291.7
  36. S.N., Chandran A., B.S., S.G., A.M., Muddebihal F., Nayyar A.S. Pulp Stones: Diagnostic Significance in Early Diagnosis and Radiographic Correlation with Ischemic Heart Diseases. Indian J Radiol Imaging. 2021; 31 (2): 277—283. PMID: 34556908
  37. Schaffner M., Stich H., Lussi A. [Denticles: dental pulp calculi]. Swiss Dent J. 2014; 124 (4): 416—7 (In German). PMID: 2480513

Received

November 24, 2022

Accepted

February 14, 2023

Published on

March 22, 2023