DOI:

10.37988/1811-153X_2018_3_58

Comparative analysis and justification of the choice of experimental models used in the study of osseointegration of dental implants

Authors

  • S.N. Khvostov 1, assistant at the Dentistry diseases propaedeutics Department
  • S.V. Poroysky 1, PhD in Medical Sciences, associate professor and head of the Disaster medicine Department
  • D.V. Mikhalchenko 1, PhD in Medical Sciences, associate professor and head of the Dentistry diseases propaedeutics Department
  • E.N. Yarygina 1, PhD in Medical Sciences, associate professor of the Oral and maxillofacial surgery Department
  • A.V. Zhidovinov 1, PhD in Medical Sciences, assistant professor of the Dentistry diseases propaedeutics Department
  • 1 Volgograd State Medical University, 400131, Volgograd, Russia

Abstract

We conducted a scientific study to compare the analysis of the experimental models used in the study of osseointegration of dental implants. Assess the possibility of participation of different animal species in the experimental part of the study of the process of osseointegration of dental implants. When planning an experiment related to the study of osseointegration of dental implants, the following criteria should be considered: the size, the possibility of surgical access, the possibility of installing the test sample, the localization for installation, the financial cost of the study, bioethical aspects. The experimental model using small cattle (sheep, sheep) best provides the necessary conditions for conducting osseointegration studies of various systems of dental implants, including TSIII SA and TSIII CA Osstem Implant systems. To select the optimal installation area for the test samples, X-ray studies, including CBCT and segmental crucibles, can be used.

Key words:

osseointegration, dental implants, experimental model

For Citation

[1]
Khvostov S.N., Poroysky S.V., Mikhalchenko D.V., Yarygina E.N., Zhidovinov A.V. Comparative analysis and justification of the choice of experimental models used in the study of osseointegration of dental implants. Clinical Dentistry (Russia).  2018; 3 (87): 58—62. DOI: 10.37988/1811-153X_2018_3_58

References

  1. Ашуев Ж.А., Кулаков А.А., Капанадзе Г.Д. Использование мини-свиней в экспериментальной имплантологии. - Биомедицина. - 2007; 6: 81-8.
  2. Михальченко Д.В., Бадрак Е.Ю., Михальченко А.В., Ярыгина Е.Н. Внутренний интерфейс дентального имплантата как очаг хронической инфекции. - Медицинский вестник Северного Кавказа. - 2015; 10 (3): 307-9.
  3. Михальченко В.Ф., Михальченко Д.В., Порошин А.В. Способ улучшения процесса остеоинтеграции дентального имплантата. - Волгоградский научно-медицинский журнал. - 2014; 3 (43): 46-9.
  4. Сирак С.В., Слетов А.А., Мартиросян А.К., Ибрагимов И.М., Перикова М.Г. Использование пористого титана для субантральной аугментации кости при дентальной имплантации (экспериментальное исследование). - Медицинский вестник Северного Кавказа. - 2013; 8 (3): 42-4.
  5. Brånemark P.I., Adell R., Breine U., Hansson B.O., Lindström J., Ohlsson A. Intra-osseous anchorage of dental prostheses. I. Experimental studies. - Scand J Plast Reconstr Surg. - 1969; 3 (2): 81-100.DOI: https://dx.doi.org/10.3109/02844316909036699
  6. Pearce A.I., Richards R., Milz S., Schneider E. Animal models for implant biomaterial research in bone: a review. - Eur Cell Mater. - 2007; 13: 1-10.
  7. Pellegrini G., Seol Y.G., GruberR., Giannobili W.V. Pre-clinical models for oral and periodontal reconstructive therapies. - J Dent Res. - 2009; 88 (12): 1065-76.
  8. Voigt J., Borysiewicz L. Uniting research into human and animal health. - Vet Rec. - 2010; 166 (13): 406-7.

Published on

September 1, 2018